Opportunity Information: Apply for HRSA 25 058

The Health Resources and Services Administration (HRSA) is offering a discretionary cooperative agreement (HRSA-25-058; CFDA 93.928) under the Ryan White HIV/AIDS Program (RWHAP) Special Projects of National Significance (SPNS) to fund a single Implementation Technical Assistance Provider (ITAP). The opportunity is centered on improving mental health outcomes and strengthening engagement and retention in HIV care for people with HIV who also have mental health conditions, especially individuals who are out of care or who face persistent barriers to staying in care. The application deadline listed is March 18, 2025, and HRSA expects to make one award. While an award ceiling is not specified in the source information provided, the funding mechanism indicates substantial involvement from the federal agency consistent with cooperative agreements.

The funded ITAP will co-lead a national initiative alongside a separately funded Evaluation Provider (EP) that is supported through a companion notice of funding opportunity (NOFO). Together, the ITAP and EP are expected to run the initiative in a coordinated way, with clear shared leadership responsibilities. At the center of the work is a national cohort of implementation sites that will be selected and supported to adapt and put into practice culturally responsive interventions that help people with co-occurring HIV and mental health conditions engage in HIV primary care and mental health services, remain connected to those services over time, and overcome practical and structural barriers that disrupt continuity of care.

The initiative lays out three main objectives. First, the ITAP will support implementation sites as they adapt and implement interventions that are responsive to culture and community context, with the explicit goal of improving engagement and retention in both HIV and mental health care. This includes hands-on technical assistance to help sites translate evidence-informed approaches into workable clinic and community workflows, and to tailor interventions to the needs of the populations they serve. When selecting implementation sites, the initiative allows applicants to identify additional priority populations, including groups highlighted in the National HIV/AIDS Strategy, so the cohort can reflect settings and communities where gaps in care and disparities are most pressing.

Second, the initiative emphasizes rigorous evaluation using implementation science frameworks. While the EP leads the evaluation function, the ITAP is expected to work closely with the EP so that implementation support and evaluation inform each other throughout the project. The evaluation is meant to capture what changes sites make to interventions (adaptations), what gets in the way or helps (barriers and facilitators), which implementation strategies are used to launch and sustain the work, what the costs look like, and a broader set of outcomes related to implementation performance, client experience, and service delivery. A key expectation is that findings will not sit at the end of the project; they will be documented and shared during the initiative so sites and the broader RWHAP community can learn in real time about what is working, for whom, and under what conditions.

Third, the ITAP and EP will help translate the initiative’s lessons into practical, user-friendly products that other RWHAP-funded organizations can actually use. The grant calls for the creation and dissemination of multimedia materials designed to support replication of effective interventions across diverse settings. In practice, that means packaging the playbook of implementation in accessible formats so programs beyond the initial cohort can adopt proven approaches to improve mental health, strengthen retention in HIV care, and ultimately improve quality of life for people with HIV.

Eligibility is limited to domestic applicants and includes a wide range of public and nonprofit entities such as state, county, and city or township governments; local health departments; academic institutions; nonprofit hospitals and outpatient clinics; community health centers supported under Section 330 of the Public Health Service Act; faith-based and community-based organizations; and Indian tribes or tribal organizations, whether federally recognized or not. “Domestic” is defined broadly to include all 50 states, Washington, DC, Puerto Rico, the Northern Mariana Islands, American Samoa, Guam, the US Virgin Islands, and several US-affiliated Pacific jurisdictions (the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau). Individuals are not eligible to apply under this NOFO. Overall, the opportunity is designed to generate actionable, scalable guidance on how to implement strategies that reconnect people with HIV and mental health conditions to care, keep them engaged, and improve both mental health and HIV outcomes across different communities and service settings.

  • The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Improving Mental Health and Engagement in Care Among People with HIV — Implementation Technical Assistance Provider" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
  • This funding opportunity was created on 2025-01-16.
  • Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Others.
Apply for HRSA 25 058

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FAQs: HRSA RWHAP SPNS Implementation Technical Assistance Provider (ITAP) - HRSA-25-058 (CFDA 93.928)

What is this funding opportunity?

This is a discretionary cooperative agreement from the Health Resources and Services Administration (HRSA) under the Ryan White HIV/AIDS Program (RWHAP) Special Projects of National Significance (SPNS). The notice is HRSA-25-058 (CFDA 93.928) and it will fund one organization to serve as the Implementation Technical Assistance Provider (ITAP).

What is the main purpose of the award?

The purpose is to improve mental health outcomes and strengthen engagement and retention in HIV care for people with HIV who also have mental health conditions, with a particular emphasis on individuals who are out of care or who face persistent barriers to staying in care.

How many awards does HRSA expect to make?

HRSA expects to make one award.

What is the application deadline?

The application deadline listed is March 18, 2025.

What type of funding mechanism is being used?

The award is a cooperative agreement, which indicates substantial involvement from the federal agency in the funded project’s activities, consistent with how cooperative agreements operate.

Is an award ceiling provided in the information available here?

No. Based on the information provided, an award ceiling is not specified.

What does ITAP stand for, and what role will it play?

ITAP stands for Implementation Technical Assistance Provider. The funded ITAP will co-lead a national initiative and provide hands-on technical assistance to a cohort of implementation sites as they adapt and implement culturally responsive interventions designed to improve engagement and retention in both HIV primary care and mental health services.

Who will the ITAP work with to run the initiative?

The ITAP will co-lead the initiative alongside a separately funded Evaluation Provider (EP) that is supported through a companion notice of funding opportunity (NOFO). The ITAP and EP are expected to run the initiative in a coordinated way with clear shared leadership responsibilities.

What is the Evaluation Provider (EP), and how does it relate to this award?

The EP is a separate entity funded under a companion NOFO to lead the evaluation function for the national initiative. Even though the EP leads evaluation, the ITAP is expected to work closely with the EP so implementation support and evaluation continuously inform each other.

What is the initiative’s target population?

The initiative focuses on people with HIV who also have mental health conditions, especially individuals who are out of care or who face persistent barriers to staying in care.

What is meant by a national cohort of implementation sites?

The initiative will include a cohort of implementation sites that will be selected and supported to adapt and put into practice culturally responsive interventions aimed at improving engagement and retention in HIV and mental health care, and reducing barriers that disrupt continuity of care.

What kinds of interventions are implementation sites expected to use?

Implementation sites will adapt and implement culturally responsive, evidence-informed interventions intended to help people with co-occurring HIV and mental health conditions engage in HIV primary care and mental health services, stay connected to those services over time, and address practical and structural barriers to continuity of care.

What are the three main objectives of the initiative?

The three main objectives described are: (1) support implementation sites to adapt and implement culturally responsive interventions to improve engagement and retention in HIV and mental health care; (2) support rigorous evaluation using implementation science frameworks (led by the EP, in close coordination with the ITAP); and (3) translate lessons learned into practical, user-friendly multimedia products that help other RWHAP-funded organizations replicate effective interventions.

What does "culturally responsive" mean in the context provided?

In this opportunity, culturally responsive means interventions are adapted to be responsive to culture and community context, and tailored to the needs of the populations served by implementation sites.

What kind of technical assistance is the ITAP expected to provide?

The ITAP is expected to provide hands-on technical assistance to help sites translate evidence-informed approaches into workable clinic and community workflows and tailor interventions to local needs and the populations served.

Does the initiative allow the cohort to focus on additional priority populations?

Yes. When selecting implementation sites, the initiative allows applicants to identify additional priority populations, including groups highlighted in the National HIV/AIDS Strategy, so the cohort can reflect settings and communities where gaps in care and disparities are most pressing.

How is evaluation expected to be approached?

Evaluation is expected to be rigorous and based on implementation science frameworks. While the EP leads evaluation, the ITAP is expected to collaborate closely so that implementation activities and evaluation findings inform each other throughout the project.

What types of evaluation questions or measures are mentioned?

The evaluation is intended to capture intervention adaptations, barriers and facilitators, implementation strategies used to launch and sustain the work, costs, and a broader set of outcomes related to implementation performance, client experience, and service delivery.

How will findings be shared during the project?

A key expectation is that findings will be documented and shared during the initiative, not only at the end, so implementation sites and the broader RWHAP community can learn in real time about what is working, for whom, and under what conditions.

What kinds of products are expected from the ITAP and EP?

The grant calls for creation and dissemination of practical, user-friendly products, including multimedia materials, designed to support replication of effective interventions across diverse settings. The goal is to package implementation lessons in accessible formats for other RWHAP-funded organizations.

Who is eligible to apply?

Eligibility is limited to domestic applicants and includes public and nonprofit entities such as state, county, and city or township governments; local health departments; academic institutions; nonprofit hospitals and outpatient clinics; community health centers supported under Section 330 of the Public Health Service Act; faith-based and community-based organizations; and Indian tribes or tribal organizations (federally recognized or not).

Are individuals eligible to apply?

No. Individuals are not eligible to apply under this NOFO.

What does "domestic" mean for eligibility purposes?

Domestic is defined broadly to include all 50 states, Washington, DC, Puerto Rico, the Northern Mariana Islands, American Samoa, Guam, the US Virgin Islands, and US-affiliated Pacific jurisdictions including the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau.

Is this opportunity specifically tied to the Ryan White HIV/AIDS Program (RWHAP)?

Yes. This opportunity is offered under HRSA’s Ryan White HIV/AIDS Program (RWHAP) SPNS and is intended to generate actionable, scalable guidance for RWHAP-funded organizations and communities.

What is the overall expected impact of this initiative?

The overall aim is to generate actionable, scalable guidance on implementing strategies that reconnect people with HIV and mental health conditions to care, keep them engaged, and improve both mental health and HIV outcomes across different communities and service settings.

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