Opportunity Information: Apply for HRSA 25 058

The Health Resources and Services Administration (HRSA) is offering a discretionary cooperative agreement (HRSA-25-058; CFDA 93.928) under the Ryan White HIV/AIDS Program (RWHAP) Special Projects of National Significance (SPNS) to fund a single Implementation Technical Assistance Provider (ITAP). The opportunity is centered on improving mental health outcomes and strengthening engagement and retention in HIV care for people with HIV who also have mental health conditions, especially individuals who are out of care or who face persistent barriers to staying in care. The application deadline listed is March 18, 2025, and HRSA expects to make one award. While an award ceiling is not specified in the source information provided, the funding mechanism indicates substantial involvement from the federal agency consistent with cooperative agreements.

The funded ITAP will co-lead a national initiative alongside a separately funded Evaluation Provider (EP) that is supported through a companion notice of funding opportunity (NOFO). Together, the ITAP and EP are expected to run the initiative in a coordinated way, with clear shared leadership responsibilities. At the center of the work is a national cohort of implementation sites that will be selected and supported to adapt and put into practice culturally responsive interventions that help people with co-occurring HIV and mental health conditions engage in HIV primary care and mental health services, remain connected to those services over time, and overcome practical and structural barriers that disrupt continuity of care.

The initiative lays out three main objectives. First, the ITAP will support implementation sites as they adapt and implement interventions that are responsive to culture and community context, with the explicit goal of improving engagement and retention in both HIV and mental health care. This includes hands-on technical assistance to help sites translate evidence-informed approaches into workable clinic and community workflows, and to tailor interventions to the needs of the populations they serve. When selecting implementation sites, the initiative allows applicants to identify additional priority populations, including groups highlighted in the National HIV/AIDS Strategy, so the cohort can reflect settings and communities where gaps in care and disparities are most pressing.

Second, the initiative emphasizes rigorous evaluation using implementation science frameworks. While the EP leads the evaluation function, the ITAP is expected to work closely with the EP so that implementation support and evaluation inform each other throughout the project. The evaluation is meant to capture what changes sites make to interventions (adaptations), what gets in the way or helps (barriers and facilitators), which implementation strategies are used to launch and sustain the work, what the costs look like, and a broader set of outcomes related to implementation performance, client experience, and service delivery. A key expectation is that findings will not sit at the end of the project; they will be documented and shared during the initiative so sites and the broader RWHAP community can learn in real time about what is working, for whom, and under what conditions.

Third, the ITAP and EP will help translate the initiative’s lessons into practical, user-friendly products that other RWHAP-funded organizations can actually use. The grant calls for the creation and dissemination of multimedia materials designed to support replication of effective interventions across diverse settings. In practice, that means packaging the playbook of implementation in accessible formats so programs beyond the initial cohort can adopt proven approaches to improve mental health, strengthen retention in HIV care, and ultimately improve quality of life for people with HIV.

Eligibility is limited to domestic applicants and includes a wide range of public and nonprofit entities such as state, county, and city or township governments; local health departments; academic institutions; nonprofit hospitals and outpatient clinics; community health centers supported under Section 330 of the Public Health Service Act; faith-based and community-based organizations; and Indian tribes or tribal organizations, whether federally recognized or not. “Domestic” is defined broadly to include all 50 states, Washington, DC, Puerto Rico, the Northern Mariana Islands, American Samoa, Guam, the US Virgin Islands, and several US-affiliated Pacific jurisdictions (the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau). Individuals are not eligible to apply under this NOFO. Overall, the opportunity is designed to generate actionable, scalable guidance on how to implement strategies that reconnect people with HIV and mental health conditions to care, keep them engaged, and improve both mental health and HIV outcomes across different communities and service settings.

  • The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Improving Mental Health and Engagement in Care Among People with HIV — Implementation Technical Assistance Provider" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
  • This funding opportunity was created on 2025-01-16.
  • Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Others.
Apply for HRSA 25 058

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