Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) | PA 24 201

Opportunity Information: Apply for PA 24 201

The NIH opportunity titled "Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)" (PA-24-201) is a discretionary grant mechanism designed to quickly add funds to projects that already have an active NIH award when an emergency situation creates urgent, unexpected needs. The basic idea is not to start a brand-new standalone project, but to competitively revise an existing NIH-funded award so the current scope can be expanded, adapted, or redirected to address impacts tied to a major disaster event. The emergency trigger can be a presidentially declared disaster under the Stafford Act, a public health emergency declared by the HHS Secretary, or another local, regional, or national disaster that creates a clear and time-sensitive research, programmatic, or operational need.

A key feature of this program is that applications are only accepted when they respond to an "Emergency Notice of Special Interest" (NOSI). In practice, NIH Institutes and Centers (ICs) will publish emergency NOSIs specific to the event and the kind of work they want to support, and only applications submitted in response to one of those emergency NOSIs can be routed and considered under this funding opportunity announcement. Those applications are sent directly to the NIH awarding component that signed onto the emergency NOSI, which is NIH's way of keeping the review and funding pathway focused and fast-moving during urgent circumstances. If there is no active emergency NOSI from an NIH IC, an application cannot use this NOFO as a general-purpose supplement request.

The "clinical trial optional" label means a proposed revision may include clinical trial activities if the relevant emergency NOSI and the parent award context allow it, but a clinical trial is not required. In other words, the mechanism is flexible enough to support a range of emergency-related needs, from clinical and public health responses to other urgent, disaster-driven research or capacity requirements, as long as the request is tied to an existing NIH award and fits the specific emergency NOSI instructions.

Eligibility is broad and includes many of the standard applicant types NIH works with. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. NIH also highlights additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-domestic (non-U.S.) entities (foreign organizations), reflecting the reality that disasters and public health emergencies can have cross-jurisdictional and international dimensions.

The opportunity sits in NIH funding activity categories that include education, environment, and health, and it is associated with multiple CFDA (Assistance Listing) numbers: 93.113, 93.142, 93.143, 93.279, 93.307, and 93.846. The posting date is April 18, 2024, and the listed closing date is April 18, 2027, which generally signals a standing mechanism that can be used whenever NIH issues emergency NOSIs during that period rather than a single one-time deadline for one event. Specific award amounts are not spelled out in the provided listing (the award ceiling and expected awards fields are blank), which is typical for emergency supplement structures where budget size and the number of awards often depend on the scale of the emergency, the amount of emergency funding available, and the volume and quality of requests received.

Overall, this NOFO is best understood as NIH's emergency "on-ramp" for quickly modifying and bolstering existing NIH-funded projects to meet urgent disaster-related needs, with access controlled through event-specific emergency NOSIs and with flexibility to include clinical trials when appropriate.

• The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.142, 93.143, 93.279, 93.307, 93.846.
• This funding opportunity was created on 2024-04-18.
• Applicants must submit their applications by 2027-04-18.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PA 24 201

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