Opportunity Information: Apply for CDC RFA CE 25 0114
The Drug-Free Communities (DFC) Support Program - NEW (Year 1) (Funding Opportunity Number CDC RFA CE 25 0114) is a discretionary federal grant program jointly supported by the Office of National Drug Control Policy (ONDCP) and the Centers for Disease Control and Prevention (CDC), specifically CDC's National Center for Injury Prevention and Control (NCIPC). Authorized under the Drug-Free Communities Act of 1997 (Public Law 105-20), this FY 2025 funding opportunity is designed to help communities launch or strengthen local, community-led coalition work focused on preventing youth substance use.
At its core, the program exists to build and reinforce collaboration in a community so that prevention is not handled by one organization alone, but instead coordinated across many sectors. The statute sets out two main goals. First, it aims to establish and strengthen cooperation among community groups, public and private nonprofit agencies, and federal, state, local, and tribal partners to support coalitions working to prevent and reduce substance use among youth ages 18 and under. Second, it aims to reduce youth substance use and, over time, reduce adult substance use as well, by focusing on the local conditions that drive risk (things that make substance use more likely) and increasing protective factors (things that help youth avoid or delay use). In practice, that means the program is oriented toward community-level change: aligning schools, families, youth-serving organizations, public health, law enforcement, local government, healthcare, and other partners around a shared prevention plan rather than isolated activities.
This "NEW (Year 1)" competition is specifically aimed at coalitions that have not previously received a DFC grant. The intended applicants are community-based coalitions addressing youth substance use, with a coalition defined in the notice as a formal arrangement where multiple community sectors agree to work together toward a common goal of a safe, healthy, drug-free community while each sector maintains its own identity. The application can be submitted by the coalition itself or by a legal applicant applying on the coalition's behalf (an organization applying on behalf of a coalition, the coalition, or the applicant coalition). In all cases, the legal applicant must be located in the United States or U.S. territories.
Eligibility is broad, but it is anchored in the idea that the applicant must be a legitimate domestic organization connected to a community coalition. The notice includes nonprofits (including 501(c)(3) organizations and other 501(c) entities), and it also allows a range of public and community entities when appropriate, including state, county, city or township governments, special district governments, independent school districts, federally recognized tribal governments, tribal organizations, and other community-based entities. The eligibility section also explicitly cites examples such as state-recognized tribes, urban Indian organizations (as defined in Public Law 94-437), public or private colleges and universities, professional associations, voluntary organizations, self-help groups, consumer and provider constituency groups, community- and faith-based organizations, and tribal organizations, consistent with Public Law 114-198 Section 103. The key limiting factor for this particular competition is not organizational type alone, but whether the coalition is truly community-based and has not previously been funded through DFC.
Funding details in the posted source indicate an award ceiling of $125,000, with an expectation of about 50 awards. The opportunity is classified under the health funding activity category and is associated with CFDA number 93.276. The application deadline listed is May 5, 2025, and the opportunity record shows a creation date of March 19, 2025. Overall, this grant is meant to support the early stage (Year 1) of DFC participation for new coalitions by helping them organize cross-sector partners, coordinate a prevention strategy, and pursue measurable reductions in youth substance use by changing community-level risks and strengthening protective conditions over time.Apply for CDC RFA CE 25 0114
- The Centers for Disease Control - NCIPC in the health sector is offering a public funding opportunity titled "Drug-Free Communities (DFC) Support Program - NEW (Year 1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.276.
- This funding opportunity was created on 2025-03-19.
- Applicants must submit their applications by 2025-05-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $125,000.00 in funding.
- The number of recipients for this funding is limited to 50 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Others, Unrestricted.
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| Funding Opportunity |
|---|
| Drug-Free Communities (DFC) Support Program - Competing Continuation (Year 6) Apply for CDC RFA CE20 20040601CONT25 Funding Number: CDC RFA CE20 20040601CONT25 Agency: Centers for Disease Control - NCIPC Category: Health Funding Amount: $125,000 |
| Tribal Management Grant Program Apply for HHS 2025 IHS TMD 0002 Funding Number: HHS 2025 IHS TMD 0002 Agency: Indian Health Service Category: Health Funding Amount: $150,000 |
| Native Hawaiian Health Scholarship Program Administrative Support Apply for HRSA 25 073 Funding Number: HRSA 25 073 Agency: Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
| Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional) Apply for PAR 25 438 Funding Number: PAR 25 438 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| FY 2025 Competitive Grant Solicitation Anti-Doping Activities Apply for ADA ADA 25 002 Funding Number: ADA ADA 25 002 Agency: Office of National Drug Control Policy Category: Health Funding Amount: $14,000,000 |
| First Responders – Comprehensive Addiction and Recovery Act Apply for TI 25 001 Funding Number: TI 25 001 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $800,000 |
| Suicide Prevention Resource Center Apply for SM 25 012 Funding Number: SM 25 012 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $10,207,289 |
| Treatment and Recovery Services for Youth, Young Adults, and Families Apply for TI 25 003 Funding Number: TI 25 003 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $545,000 |
| Targeted Capacity Expansion – Special Projects Apply for TI 25 002 Funding Number: TI 25 002 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $375,000 |
| National Technical Assistance Center for Child, Youth and Family Mental Health Apply for SM 25 020 Funding Number: SM 25 020 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $5,075,000 |
| NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed) Apply for PAR 25 333 Funding Number: PAR 25 333 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| National Alzheimers Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA AG 26 003 Funding Number: RFA AG 26 003 Agency: National Institutes of Health Category: Health Funding Amount: $10,350,000 |
| NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional) Apply for RFA RM 25 002 Funding Number: RFA RM 25 002 Agency: National Institutes of Health Category: Health Funding Amount: $475,000 |
| NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional) Apply for RFA RM 25 001 Funding Number: RFA RM 25 001 Agency: National Institutes of Health Category: Health Funding Amount: $700,000 |
| NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) Apply for RFA RM 25 003 Funding Number: RFA RM 25 003 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed) Apply for PAR 25 416 Funding Number: PAR 25 416 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional) Apply for RFA OD 25 008 Funding Number: RFA OD 25 008 Agency: National Institutes of Health Category: Health Funding Amount: $75,000 |
| Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed) Apply for PAR 25 437 Funding Number: PAR 25 437 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Studies (U01 Clinical Trial Not Allowed) Apply for RFA AR 25 013 Funding Number: RFA AR 25 013 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UH3 Clinical Trial Optional) Apply for RFA AR 25 014 Funding Number: RFA AR 25 014 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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